What is Myoglobin ?


Myoglobin is a respiratory pigment present in skeletal muscle. Its Structure is similar to a single subunit of the hemoglobin molecule; it contains only one iron ion has a molecular weight of about 17000. Its affinity for O2 is greater than that of hemoglobin and therefore, it picks oxygen from hemoglobin. It releases its oxygen only when the partial pressure Po2 in the skeletal muscle falls below 20mm HG. 

When the muscle is at rest or engaged in only moderate activity, the myoglobin holds on to its oxygen. During rigorous exercise ,when the muscle cells use oxygen rapidly and partial pressure of the oxygen in the muscle drops to zero, myoglobin realese its oxygen. Thus, Myoglobin provides an additional reserve of oxygen for active muscles. 

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